The effectiveness of oral clonidine as a sedative/anxiolytic anx as a drug to blunt the hemodynamic responses to laryngoscopy

CE Laurito, VL Baughman, GL Becker… - Journal of Clinical …, 1991 - Elsevier
Abstract Study Objective: To determine the effects of oral clonidine premeditation sedative,
anxiolytic, and hemodynamic responses during the immediate preoperative period,
laryngoscopy/intubation, and postanesthetic recovery. Design: Randomized double-blind
assignment to one of four treatment groups (clonidine 0.1 mg, clonidine 0.2 mg, triazolam
0.25 mg, or placebo); n= 10 per group. Setting: Inpatient surgery in a university-staffed
tertiary center. Patients: Forty ASA physical status I and II adults of both sexes scheduled, for …
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